Everspan organizes published research for informational purposes only. This is not medical advice. Consult a healthcare provider before starting any intervention.

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BPC-157520·Semaglutide (GLP-1 Agonist)470·Rapamycin (Sirolimus)450·Nicotinamide Mononucleotide (NMN)410·Metformin380·Creatine Monohydrate340·Ashwagandha (KSM-66)290·Nicotinamide Riboside (NR)280·Vitamin D3260·Time-Restricted Eating (Intermittent Fasting)250·Cold Exposure (Cold Plunge/Shower)240·Omega-3 Fatty Acids (EPA/DHA)230·Sauna Use (Finnish-style)220·NAD+ IV Infusion210·Stem Cell Therapy200·Berberine190·Epithalon (Epitalon)180·Fisetin160·BPC-157520·Semaglutide (GLP-1 Agonist)470·Rapamycin (Sirolimus)450·Nicotinamide Mononucleotide (NMN)410·Metformin380·Creatine Monohydrate340·Ashwagandha (KSM-66)290·Nicotinamide Riboside (NR)280·Vitamin D3260·Time-Restricted Eating (Intermittent Fasting)250·Cold Exposure (Cold Plunge/Shower)240·Omega-3 Fatty Acids (EPA/DHA)230·Sauna Use (Finnish-style)220·NAD+ IV Infusion210·Stem Cell Therapy200·Berberine190·Epithalon (Epitalon)180·Fisetin160·

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Epigenetic Clock

DNA methylation clocks (Horvath, Levine PhenoAge, DunedinPACE) measure biological age independently of chronological age. Lifestyle choices can push your biological age years younger or years older than your birth certificate. Hover any dot to explore a lifestyle profile.

Biological Age vs. Chronological Age

Epigenetic clock (Horvath / DunedinPACE). Points above the line = aging faster; below = aging slower.

Hover any dot to see profile details

Longevity-Optimized Protocol-12y

Blue Zone Lifestyle-11y

Caloric Restriction Practitioner-9y

Marathon Runner, Med Diet-7y

Average American+4y

Chronically Sleep-Deprived+8y

+4 more…

−14y

Max biological age reduction documented

+14y

Worst-case acceleration (smoking + poor diet)

28y

Total spread between best and worst

Interventions that reduce epigenetic age

B+Caloric Restriction B-Rapamycin B+Zone 2 Cardio B+Sleep Optimization B+TRE / Fasting B+Metformin