Psyllium Husk Fiber
A soluble fiber supplement that research indicates supports digestive health and may modestly improve cardiovascular markers.
Human Trials
47
3,420 participants
Risk Level
Monthly Cost
Based on 10-15g daily dosing
Quick Facts
- Category
- Supplement
- Research Field
- Supplements
- Evidence Grade
- A – Strong
- Risk Level
- Low
- Monthly Cost
- $8 – $25
- Human Trials
- 47
Typical Dose
5–10 g before 1–2 meals daily
Range
5–30 g/day in divided doses
For informational purposes only – not medical advice. See disclaimer
Research Velocity
Mechanism of Action
Psyllium husk contains mucilage that forms a viscous gel when mixed with water in the digestive tract. This gel increases stool bulk and water content, facilitating regular bowel movements. The soluble fiber also binds to bile acids and cholesterol in the intestine, potentially reducing cholesterol absorption and promoting bile acid synthesis from cholesterol stores.
Overview
Psyllium husk is a soluble fiber derived from the seeds of Plantago ovata that has been extensively studied for its effects on digestive health and cardiovascular markers. Research indicates that psyllium supplementation can effectively treat constipation by increasing stool bulk and water content, while also supporting regularity in healthy individuals. Multiple randomized controlled trials have demonstrated that daily psyllium intake can modestly reduce LDL cholesterol levels, typically by 5-15%, making it a useful adjunct to dietary interventions for cardiovascular health.
Beyond its established digestive and cholesterol-lowering effects, emerging research suggests psyllium may influence the gut microbiome composition and provide modest benefits for blood sugar control in people with diabetes. Studies indicate that the gel-forming properties of psyllium can slow gastric emptying and glucose absorption, potentially contributing to better glycemic control. The supplement is generally well-tolerated when taken with adequate water, though some individuals may experience initial bloating or gas as their digestive system adapts to increased fiber intake.
Known Interactions
- May reduce absorption of medications if taken simultaneously - separate dosing by 2+ hours recommended
- Can affect blood sugar levels - may require diabetes medication adjustments
- May enhance effects of cholesterol-lowering medications
- Requires adequate water intake to prevent intestinal blockage
Legal Status by Country
Your country (United States)
Available without prescription in:
Australia, Brazil, Canada, China, Colombia, Germany, India, Israel, Japan, Mexico, Netherlands, Panama, Russia, South Korea, Switzerland, Thailand, Turkey, UAE, United Kingdom, United States
📍 = your selected country · ✈️ = medical tourism destination · Always verify current local regulations before travel.
Key Research
- 2000Cholesterol-lowering effects of psyllium intake adjunctive to diet therapy in men and women with hypercholesterolemia: meta-analysis of 8 controlled trials
Meta-analysis of cholesterol effects
- 1999The effects of psyllium on lipoproteins in type II diabetic patients
Diabetes applications
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Last verified: 2026-03-16