Everspan organizes published research for informational purposes only. This is not medical advice. Consult a healthcare provider before starting any intervention.
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Protocol Library

Compare publicly documented longevity protocols. See what top practitioners and the community are actually using.

A comprehensive, data-driven protocol covering diet, exercise, sleep, and over 100 supplements and pharmaceuticals. One of the most aggressive publicly documented longevity regimens.

20

Interventions

B

Avg. Evidence

$13304720

/month

T1: 5T2: 12T3: 3

Outlive Framework

by Peter Attia

Deep-dive

A medicine 3.0 approach emphasizing exercise as the most potent longevity drug, with focus on zone 2 cardio, strength training, stability, and targeted pharmacology.

13

Interventions

B+

Avg. Evidence

$4721880

/month

T1: 6T2: 5T3: 2

Huberman Essentials

by Andrew Huberman

Deep-dive

Science-based protocols for optimizing sleep, focus, and overall health. Emphasizes light exposure, cold exposure, and targeted supplementation.

13

Interventions

B+

Avg. Evidence

$1631345

/month

T1: 4T2: 9

Standard Biohacker Stack

by Community Consensus

Deep-dive

The most commonly adopted interventions across longevity-focused communities on Reddit and biohacker forums. Represents a moderate, well-evidenced starting point.

9

Interventions

B+

Avg. Evidence

$118905

/month

T1: 4T2: 5

Longevity Basics

by Everspan Editorial

Deep-dive

The highest-evidence, lowest-cost, safest starting point for anyone new to longevity. Only Tier 1–2 interventions with Grade A or B+ evidence. No pharmaceuticals.

13

Interventions

A

Avg. Evidence

$4281915

/month

T1: 9T2: 4

Compounds that extended lifespan in genetically diverse mice through the National Institute on Aging's rigorous Interventions Testing Program – the gold standard for pre-human longevity compound testing.

6

Interventions

B

Avg. Evidence

$3261340

/month

T3: 6

Intermittent senolytic cycles targeting clearance of senescent cells – the 'zombie cells' that accumulate with age and drive inflammation. Based on published clinical trial protocols.

4

Interventions

C+

Avg. Evidence

$1519025920

/month

T2: 2T3: 1T4: 1

NAD+ Restoration Stack

by Sinclair Lab / Community

Deep-dive

A stack focused on restoring NAD+ levels that decline with age, based on David Sinclair's research and widely adopted biohacker community protocols.

6

Interventions

B-

Avg. Evidence

$9352890

/month

T2: 3T3: 3